![]() #Project management by k nagarajan pdf printer driverWith the discovery of driver genes, non-small cell lung cancer is subdivided including adenocarcinoma, squamous cell carcinoma, large cell carcinoma, and the other unspecified. In accordance with histological type, lung cancer can be departed into two main subtypes, small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). Certainly, about 8% of lung cancer is the consequence of genetic factors that enhance the risk of disease occurring. The incidence of lung cancer primarily results from long-term tobacco smoking (85%), while there are about 10%–15% of patients who have never smoked, in that non-smokers may be exposed to second-hand smoke, radon gas, asbestos, air pollution, and so on. Now, we will review the landscape of driver genes in NSCLC including the characteristics, detection methods, the application of target therapy and challenges.īy far, the number one with the increasingly rapid incidence rate worldwide among all tumors is lung cancer, which has the highest morbidity rate. Of course, the targeted therapies based on driver genes provide a more exact option for advanced non-small cell lung cancer, improving the survival rate of patients. Over the past years, our comprehensive knowledge about the molecular biology of NSCLC has been rapidly enriching, which has promoted the discovery of driver genes in NSCLC and directed FDA-approved targeted therapies. The large number of lung cancer cases is non-small cell lung cancer (NSCLC), which approximately accounting for 75% of lung cancer. Lung cancer is one of the most common causes of cancer-related death in the world. Received: FebruAccepted: MaPublished: April 10, 2017 ![]() Hu-Qin Zhang, email: He, email: driver genes, non-small cell lung cancer, characteristics, detection methods, targeted therapies ![]() ![]() *These authors contributed equally to the work Qing-Ge Zhu 1, *, Shi-Ming Zhang 1, *, Xiao-Xiao Ding 1, *, Bing He 1 and Hu-Qin Zhang 1ġThe Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an 710049, P.R. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |